Tillinghast, J., Drury, S., Bowser, D., Benn, A., and Lee, K.P.K. (2021). Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2. Molecular Cell 81(22), 4650-4662.e4., doi:10.1016/j.molcel.2021.10.002. (Featured in press releases: here, here and here)

Zhou, Y., Nwokonko, R.M., Baraniak, J.H., Jr., Trebak, M., Lee, K.P.K., and Gill, D.L. (2019). The remote allosteric control of Orai channel gating. PLoS Biol 17, e3000413, doi:10.1371/journal.pbio.3000413.

Lee, K.P.K., Chen, J., and MacKinnon, R. (2017). Molecular structure of human KATP in complex with ATP and ADP. Elife 6, doi:10.7554/eLife.32481.

Sanches, M., Duffy, N.M., Talukdar, M., Thevakumaran, N., Chiovitti, D., Canny, M.D., Lee, K.P.K., Kurinov, I., Uehling, D., Al-awar, R., et al. (2014). Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors. Nat Commun 5, 4202, doi:10.1038/ncomms5202.

Lee, K.P.K., and Sicheri, F. (2011). Principles of IRE1 modulation using chemical tools. Methods Enzymol 490, 271-294, doi:10.1016/B978-0-12-385114-7.00016-7.

Wiseman, R.L.*, Zhang, Y.*, Lee, K.P.K.*, Harding, H.P., Haynes, C.M., Price, J., Sicheri, F., and Ron, D. (2010). Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol Cell 38, 291-304, doi:10.1016/j.molcel.2010.04.001.

Lee, K.P.K., Dey, M., Neculai, D., Cao, C., Dever, T.E., and Sicheri, F. (2008). Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. Cell 132, 89-100, doi:10.1016/j.cell.2007.10.057.

Sajic, R., Lee, K.P.K., Asai, K., Sakac, D., Branch, D.R., Upton, C., and Cochrane, A. (2007). Use of modified U1 snRNAs to inhibit HIV-1 replication. Nucleic Acids Res 35, 247-255, doi:10.1093/nar/gkl1022.

(* indicates equal contribution)